![]() One kit contained a lancet with instructions to collect a small blood sample via fingerstick. One hundred and fifty-one pregnant women (average gestational age of 9.59 weeks) received two SneakPeek Gender At-Home Test kits. After reviewing the instructional manuals and videos provided with the respective kits, study participants either self-collected their blood samples or received assistance from another individual. Participants in both groups provided informed consent to provide blood samples. Gateway Genomics conducted both at-home and clinical sample collection to compare the performance of Snap blood collection device versus lancet-fingerstick and venipuncture collection methods. We also investigated the performance of the SneakPeek Early Gender DNA Test when blood was collected using a Snap device. 7In this study we sought to determine whether the Snap blood collection device could be useful for self-collection of maternal blood in the home and in a clinical setting. 6 Additionally, blood volume beyond 300 ul can be challenging for a user. Several studies have documented that hemolysis of blood cells was caused by the shear stress of the frictional force when blood cells are vacuumed into the microcapillaries of the Snap device upon activation. 3Īs with all microsampling techniques, the Snap device has some limitations. ![]() 5 The Snap device, on the other hand, utilizes both microneedles that are significantly thinner (about the thickness of an eyelash) than lancets to pierce the skin and capillary action, in conjunction with vacuum extraction, to painlessly collect the individual’s blood. 4 While venous blood draws provide the proper amount of blood volume, the technique’s “success rate relies heavily on clinician experience and patient physiology,” and thus, patients can be bruised due to needle misses and ruptured veins. Lancet finger sticks are notable in that they often result in suboptimal quantities of blood, environmental contaminants, and the level of pain they inflict. Pain is an important factor to consider when comparing blood collection methods. ![]() The automated and self-contained nature of the device helps to standardize the blood collection process between different settings, while minimizing the risk of human error and contamination by exogenous DNA. 3 Therefore, the quality of the blood drawn is not dependent on the phlebotomist’s skill or the accessibility of the patients’ veins. Importantly, the Snap device does not require a professionally trained phlebotomist as the device is self-administered, automated, and self-contained. 3Ī novel blood collection device (“SneakPeek Snap”) developed for Gateway Genomics by Seventh Sense Biosystems offers a blood collection method that is “simple, safe, standardized, and painless.” 3 The quality of the blood drawn is on par to that of venipuncture-collected blood and can collect up to 1 ml of blood. Unfortunately, blood sample collection techniques have remained unchanged, with venous blood collected via venipuncture and capillary blood collected with a lancet finger stick being the most common methods. 2 Current NIPT requires a maternal blood sample for testing, a significant improvement over prior prenatal tests that required amniotic fluid or chorionic villi. ![]() 1 These advances have reduced the need for expensive and invasive techniques, such as chorionic villus sampling and amniocentesis, and minimized the risk for both mother and fetus. In the past decade, clinical diagnosis and personalized medicine has evolved, making affordable and accurate non-invasive prenatal testing (NIPT) a reality for many expecting parents to determine the fetus’s sex as early as 8 weeks gestation. Notably, blood samples collected using the Snap device were shown to be highly accurate for fetal sex determination - with an accuracy greater than 99%. Our data confirms that, compared to lancet finger sticks, the SneakPeek Snap device provides users several advantages including significant reduction in perceived pain, greater ease of use, a shorter sample collection time, and a dramatic reduction in risk of sample contamination. In this study, Gateway Genomics, the leading provider of fetal sex testing, introduces “SneakPeek Snap”, a novel microneedle-based, self-administered blood collection device that simplifies at-home blood collection for fetal sex testing. The advancement of prenatal DNA technology and growing demand for early fetal sex determination have created a need for a simple and easy-to-use blood collection device that eliminates the pain and difficulty individuals encounter when utilizing traditional methods of blood collection such as venipuncture or lancet fingerstick. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |